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{"id":4480,"date":"2024-11-19T13:26:15","date_gmt":"2024-11-19T13:26:15","guid":{"rendered":"https:\/\/weedhuis.com\/?post_type=product&p=4480"},"modified":"2024-11-19T13:28:57","modified_gmt":"2024-11-19T13:28:57","slug":"bretazenil","status":"publish","type":"product","link":"https:\/\/weedhuis.com\/de\/produkt\/bretazenil\/","title":{"rendered":"Bretazenil"},"content":{"rendered":"

Bretazenil (Ro16-6028) ist ein Imidazopyrrolobenzodiazepin-Anxiolytikum, das aus der Familie der Benzodiazepine stammt und 1988 erfunden wurde. Es ist in seiner Struktur am engsten mit dem GABA-Antagonisten Flumazenil verwandt, obwohl seine Wirkungen etwas anders sind. Aufgrund seiner hohen Affinit\u00e4t zur Bindung an Benzodiazepin-Bindungsstellen, wo es als partieller Agonist wirkt, wird es als hochpotentes Benzodiazepin eingestuft, dessen Profil als partieller Agonist und pr\u00e4klinische Studiendaten darauf hindeuten, dass es ein geringeres Nebenwirkungsprofil haben k\u00f6nnte. Insbesondere wurde vorgeschlagen, dass Bretazenil eine weniger starke Entwicklung von Toleranz und Entzugssyndrom verursacht.<\/p>","protected":false},"excerpt":{"rendered":"

IUPAC-Name: <\/strong>tert-Butyl-8-bromo-11,12,13,13a-tetrahydro-9-oxo-9H-imidazo(1,5-a)-pyrrolo(2,1-c)(1,4)benzodiazepin-1-carboxylat<\/p>\n

CAS # <\/strong>84379-13-5<\/p>\n

Erscheinungsbild: <\/strong>Pulver<\/p>\n

NMR-Analyse: <\/strong>C19H20BrN3O3<\/p>","protected":false},"featured_media":4481,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[593],"product_tag":[],"class_list":{"0":"post-4480","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-benzodiazepines","7":"desktop-align-left","8":"tablet-align-left","9":"mobile-align-left","11":"first","12":"instock","13":"shipping-taxable","14":"purchasable","15":"product-type-variable"},"yoast_head":"\nBretazenil - 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